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MicroRNA-21 promotes TGF-β1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression

This study aimed to explore the effects of miR-21 and PTEN/Akt signaling pathway on TGF-β1-induced epithelial-mesenchymal transition (EMT) in gastric cancer (GC). GC tissues and adjacent tissues were collected from 83 patients. The qRT-PCR assay was performed to detect miR-21 expression. The express...

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Detalles Bibliográficos
Autores principales: Li, Chang, Song, Lei, Zhang, Zhuo, Bai, Xiao-Xue, Cui, Ming-Fu, Ma, Lian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341852/
https://www.ncbi.nlm.nih.gov/pubmed/27611950
http://dx.doi.org/10.18632/oncotarget.11888