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Tumor-specific CD4(+) T cells eradicate myeloma cells genetically deficient in MHC class II display

CD4(+) T cells have been shown to reject tumor cells with no detectable expression of major histocompatibility complex class II (MHC II). However, under certain circumstances, induction of ectopic MHC II expression on tumor cells has been reported. To confirm that CD4(+) T cell-mediated anti-tumor i...

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Detalles Bibliográficos
Autores principales: Tveita, Anders, Fauskanger, Marte, Bogen, Bjarne, Haabeth, Ole Audun Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341866/
https://www.ncbi.nlm.nih.gov/pubmed/27626487
http://dx.doi.org/10.18632/oncotarget.11946