TGF-β1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis

Transforming growth factor-beta 1 (TGF-β1) suppresses T cell function, promoting tumor immune escape. Yet, whether the depression of TGF-β1 on T cell function is mediated by co-inhibitory molecules B7-H3 and B7-H4 remains largely unclear. Here, we demonstrated that TGF-β1 elevated the expression of...

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Detalles Bibliográficos
Autores principales: Zhou, Xinru, Mao, Yong, Zhu, Jianjie, Meng, Fanyi, Chen, Qi, Tao, Lihua, Li, Rui, Fu, Fengqing, Liu, Cuiping, Hu, Yuanjia, Wang, Weipeng, Zhang, Hongjian, Hua, Dong, Chen, Weichang, Zhang, Xueguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341868/
https://www.ncbi.nlm.nih.gov/pubmed/27626488
http://dx.doi.org/10.18632/oncotarget.11950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341868/
https://www.ncbi.nlm.nih.gov/pubmed/27626488
http://dx.doi.org/10.18632/oncotarget.11950

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