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A directly negative interaction of miR-203 and ZEB2 modulates tumor stemness and chemotherapy resistance in nasopharyngeal carcinoma

miR-203 is a tumor suppressor that is disregulated in numerous malignancies including nasopharyngeal carcinoma (NPC). However, the role of miR-203 in suppressing tumor stemness, chemotherapy resistance as well as its molecular mechanisms are unclear. In this study, we observed that miR-203 suppresse...

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Detalles Bibliográficos
Autores principales: Jiang, Qingping, Zhou, Ying, Yang, Huiling, Li, Libo, Deng, Xiaojie, Cheng, Chao, Xie, Yingying, Luo, Xiaojun, Fang, Weiyi, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341875/
https://www.ncbi.nlm.nih.gov/pubmed/27589832
http://dx.doi.org/10.18632/oncotarget.11691