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HLA-E expression and its clinical relevance in human renal cell carcinoma

The non-classical human leukocyte antigen E (HLA-E) expression is frequently overexpressed in tumor diseases, transplants and virus-infected cells and represents an immunomodulatory molecule by binding to the receptors CD94/NKG2A, -B and –C on NK and T cells. Due to its immune suppressive features H...

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Detalles Bibliográficos
Autores principales: Seliger, Barbara, Jasinski-Bergner, Simon, Quandt, Dagmar, Stoehr, Christine, Bukur, Juergen, Wach, Sven, Legal, Wolfgang, Taubert, Helge, Wullich, Bernd, Hartmann, Arndt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341881/
https://www.ncbi.nlm.nih.gov/pubmed/27589686
http://dx.doi.org/10.18632/oncotarget.11744