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Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush

Chronic neuro-inflammation is involved in the death of retinal ganglion cells (RGCs) in glaucoma. The aim of this study is to determine whether wogonin can suppress inflammatory responses and rescue RGCs death after optic nerve crush (ONC), an ideal animal model of glaucoma. Wogonin was administered...

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Detalles Bibliográficos
Autores principales: Xu, Yue, Yang, Boyu, Hu, Yaguang, Lu, Lin, Lu, Xi, Wang, Jiawei, Xu, Fan, Yu, Shanshan, Huang, Jingjing, Liang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341925/
https://www.ncbi.nlm.nih.gov/pubmed/27756890
http://dx.doi.org/10.18632/oncotarget.12700