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Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush
Chronic neuro-inflammation is involved in the death of retinal ganglion cells (RGCs) in glaucoma. The aim of this study is to determine whether wogonin can suppress inflammatory responses and rescue RGCs death after optic nerve crush (ONC), an ideal animal model of glaucoma. Wogonin was administered...
Autores principales: | Xu, Yue, Yang, Boyu, Hu, Yaguang, Lu, Lin, Lu, Xi, Wang, Jiawei, Xu, Fan, Yu, Shanshan, Huang, Jingjing, Liang, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341925/ https://www.ncbi.nlm.nih.gov/pubmed/27756890 http://dx.doi.org/10.18632/oncotarget.12700 |
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