Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells

Glucorticoids (GCs) such as dexamethasone (DEX) remain important treatments for Chronic Lymphocytic Leukemia (CLL) but the mechanisms are poorly understood and resistance is inevitable. Proliferation centers (PC) in lymph nodes and bone marrow offer protection against many cytotoxic drugs and circul...

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Detalles Bibliográficos
Autores principales: Oppermann, Sina, Lam, Avery J., Tung, Stephanie, Shi, Yonghong, McCaw, Lindsay, Wang, Guizhei, Ylanko, Jarkko, Leber, Brian, Andrews, David, Spaner, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341931/
https://www.ncbi.nlm.nih.gov/pubmed/27579615
http://dx.doi.org/10.18632/oncotarget.11618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341931/
https://www.ncbi.nlm.nih.gov/pubmed/27579615
http://dx.doi.org/10.18632/oncotarget.11618

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