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IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model

Cells that are able to localize β-actin mRNA efficiently have decreased metastatic potential. Invasive carcinoma cells derived from primary mammary tumors have reduced levels of an RNA binding protein IMP1/ZBP1/IGF2BP1, required for β-actin mRNA localization. We showed previously that in human breas...

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Detalles Bibliográficos
Autores principales: Nwokafor, Chiso U., Sellers, Rani S., Singer, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341935/
https://www.ncbi.nlm.nih.gov/pubmed/27655671
http://dx.doi.org/10.18632/oncotarget.12083