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IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model
Cells that are able to localize β-actin mRNA efficiently have decreased metastatic potential. Invasive carcinoma cells derived from primary mammary tumors have reduced levels of an RNA binding protein IMP1/ZBP1/IGF2BP1, required for β-actin mRNA localization. We showed previously that in human breas...
Autores principales: | Nwokafor, Chiso U., Sellers, Rani S., Singer, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341935/ https://www.ncbi.nlm.nih.gov/pubmed/27655671 http://dx.doi.org/10.18632/oncotarget.12083 |
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