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Long non-coding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and C-IAP1 complexes to activating PI3K-AKT pathway

Deleted in malignant brain tumors 1 (DMBT1) is deleted during cancer progression and as a potential tumor-suppressor gene in various types of cancer. However, its role in Gallbladder cancer remains poorly understood. DMBT1 has low-expression and deletion of copy number were detected in normal tissue...

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Detalles Bibliográficos
Autores principales: Shen, Sheng, Liu, Han, Wang, Yueqi, Wang, Jiwen, Ni, Xiaolin, Ai, Zhilong, Pan, Hongtao, Liu, Houbao, Shao, Yebo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341947/
https://www.ncbi.nlm.nih.gov/pubmed/27637083
http://dx.doi.org/10.18632/oncotarget.12023