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Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immune-stimulating activity on peripheral blood immune cells

Glucose-regulated protein94 (Grp94), the most represented endoplasmic reticulum (ER)-resident heat shock protein (HSP), is a tumor antigen shared by different types of solid and hematological tumors. The tumor-specific feature of Grp94 is its translocation from the ER to the cell surface where it di...

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Detalles Bibliográficos
Autores principales: Tramentozzi, Elisa, Ruli, Erlis, Angriman, Imerio, Bardini, Romeo, Campora, Michela, Guzzardo, Vincenza, Zamarchi, Rita, Rossi, Elisabetta, Rugge, Massimo, Finotti, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341954/
https://www.ncbi.nlm.nih.gov/pubmed/27662661
http://dx.doi.org/10.18632/oncotarget.12141