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Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

BACKGROUND: Genetic alterations on chromosome 9p, including inactivation of the tumour suppressor gene, CDKN2A, result in cellular proliferation and growth of tumours. Our aim was to use microsatellite analysis and fluorescence in situ hybridization (FISH) to characterise the architecture of this re...

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Detalles Bibliográficos
Autores principales: El-Mokadem, Ismail, Kidd, Thomas, Pratt, Norman, Fleming, Stewart, Nabi, Ghulam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341962/
https://www.ncbi.nlm.nih.gov/pubmed/27682877
http://dx.doi.org/10.18632/oncotarget.12196