Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation

Obesity is an important risk factor for exacerbating chronic diseases such as cardiovascular disease and cancer. High serum level of saturated free fatty acids such as palmitate is an important contributor for obesity-induced diseases. Here, we examined the contribution of inflammasome activation in...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Chen, Yang, Li, Xiang, Zhang, Youzhi, Gulbins, Erich, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341975/
https://www.ncbi.nlm.nih.gov/pubmed/27689324
http://dx.doi.org/10.18632/oncotarget.12302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341975/
https://www.ncbi.nlm.nih.gov/pubmed/27689324
http://dx.doi.org/10.18632/oncotarget.12302

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