Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells

Protein tyrosine kinase 7 (PTK7), a member of the catalytically defective receptor protein tyrosine kinase family, is upregulated in various cancers including esophageal squamous cell carcinoma (ESCC). Here, we have explored the molecular mechanism of PTK7-dependent invasiveness in ESCC cells. PTK7...

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Detalles Bibliográficos
Autores principales: Shin, Won-Sik, Hong, Yuri, Lee, Hae Won, Lee, Seung-Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341976/
https://www.ncbi.nlm.nih.gov/pubmed/27689325
http://dx.doi.org/10.18632/oncotarget.12303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341976/
https://www.ncbi.nlm.nih.gov/pubmed/27689325
http://dx.doi.org/10.18632/oncotarget.12303

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