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An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells

Sorafenib resistance remains a major obstacle for the effective treatment of hepatocellular carcinoma (HCC), and a number of miRNAs contribute to this resistance. However, the regulatory networks of miRNAs are very complex, thus inhibiting a single miRNA may sequentially activate other compensatory...

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Detalles Bibliográficos
Autores principales: Tang, Shuyao, Tan, Gang, Jiang, Xian, Han, Peng, Zhai, Bo, Dong, Xuesong, Qiao, Haiquan, Jiang, Hongchi, Sun, Xueying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341977/
https://www.ncbi.nlm.nih.gov/pubmed/27689326
http://dx.doi.org/10.18632/oncotarget.12304