Cargando…
An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells
Sorafenib resistance remains a major obstacle for the effective treatment of hepatocellular carcinoma (HCC), and a number of miRNAs contribute to this resistance. However, the regulatory networks of miRNAs are very complex, thus inhibiting a single miRNA may sequentially activate other compensatory...
Autores principales: | Tang, Shuyao, Tan, Gang, Jiang, Xian, Han, Peng, Zhai, Bo, Dong, Xuesong, Qiao, Haiquan, Jiang, Hongchi, Sun, Xueying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341977/ https://www.ncbi.nlm.nih.gov/pubmed/27689326 http://dx.doi.org/10.18632/oncotarget.12304 |
Ejemplares similares
-
LncRNA SNHG1 contributes to sorafenib resistance by activating the Akt pathway and is positively regulated by miR-21 in hepatocellular carcinoma cells
por: Li, Weidong, et al.
Publicado: (2019) -
Correction to: LncRNA SNHG1 contributes to sorafenib resistance by activating the Akt pathway and is positively regulated by miR-21 in hepatocellular carcinoma cells
por: Li, Weidong, et al.
Publicado: (2021) -
Dual inhibition of Akt and c‐Met as a second‐line therapy following acquired resistance to sorafenib in hepatocellular carcinoma cells
por: Han, Peng, et al.
Publicado: (2017) -
MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway
por: He, Changjun, et al.
Publicado: (2015) -
Sodium orthovanadate overcomes sorafenib resistance of hepatocellular carcinoma cells by inhibiting Na(+)/K(+)-ATPase activity and hypoxia-inducible pathways
por: Jiang, Wenjing, et al.
Publicado: (2018)