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Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics

Overexpression of Mcl-1 is implicated in resistance of several cancers to chemotherapeutic treatment, therefore identifying a safe way to decrease its expression in tumor cells represents a central goal. We investigated if a modulation of the diet could impact on Mcl-1 expression using a Myc-driven...

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Detalles Bibliográficos
Autores principales: Rubio-Patiño, Camila, Bossowski, Jozef P., Villa, Elodie, Mondragón, Laura, Zunino, Barbara, Proïcs, Emma, Chiche, Johanna, Bost, Frédéric, Verhoeyen, Els, Ricci, Jean-Ehrland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341978/
https://www.ncbi.nlm.nih.gov/pubmed/27689327
http://dx.doi.org/10.18632/oncotarget.12309