Co-application of canavanine and irradiation uncouples anticancer potential of arginine deprivation from citrulline availability

The moderate anticancer effect of arginine deprivation in clinical trials has been linked to an induced argininosuccinate synthetase (ASS1) expression in initially ASS1-negative tumors, and ASS1-positive cancers are anticipated as non-responders. Our previous studies indicated that arginine deprivat...

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Detalles Bibliográficos
Autores principales: Kurlishchuk, Yuliya, Vynnytska-Myronovska, Bozhena, Grosse-Gehling, Philipp, Bobak, Yaroslav, Manig, Friederike, Chen, Oleg, Merker, Sebastian R., Henle, Thomas, Löck, Steffen, Stange, Daniel E., Stasyk, Oleh, Kunz, Leoni A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341980/
https://www.ncbi.nlm.nih.gov/pubmed/27689335
http://dx.doi.org/10.18632/oncotarget.12320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341980/
https://www.ncbi.nlm.nih.gov/pubmed/27689335
http://dx.doi.org/10.18632/oncotarget.12320

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