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Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation

Colorectal cancer (CRC) is the second most common cause of cancer-related death, encouraging the search for novel therapeutic targets affecting tumor cell proliferation and migration. These cellular processes are under tight control of two opposing groups of enzymes; kinases and phosphatases. Aberra...

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Detalles Bibliográficos
Autores principales: Hoekstra, Elmer, Das, Asha M., Willemsen, Marcella, Swets, Marloes, Kuppen, Peter J.K., van der Woude, Christien J., Bruno, Marco J., Shah, Jigisha P., Hagen, Timo L.M. ten, Chisholm, John D., Kerr, William G., Peppelenbosch, Maikel P., Fuhler, Gwenny M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341996/
https://www.ncbi.nlm.nih.gov/pubmed/27716613
http://dx.doi.org/10.18632/oncotarget.12321