Decreased expression of IDH1-R132H correlates with poor survival in gastrointestinal cancer

Isocitrate dehydrogenase (IDH1) is an NADP-dependent enzyme that catalyzes the decarboxylation of isocitrate to alpha-ketoglutarate. The IDH1-R132H mutation predicts a better clinical outcome for glioma patients, and the expression of IDH1-R132H correlates with a favorable outcome in patients with b...

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Detalles Bibliográficos
Autores principales: Li, Jieying, Huang, Jianfei, Huang, Fang, Jin, Qing, Zhu, Huijun, Wang, Xudong, Chen, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342004/
https://www.ncbi.nlm.nih.gov/pubmed/27655638
http://dx.doi.org/10.18632/oncotarget.12039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342004/
https://www.ncbi.nlm.nih.gov/pubmed/27655638
http://dx.doi.org/10.18632/oncotarget.12039

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