Asn-Gly-Arg-modified polydopamine-coated nanoparticles for dual-targeting therapy of brain glioma in rats

The blood-brain barrier (BBB) is the major clinical obstacle in the chemotherapeutic management of brain glioma. Here we synthesized a pH-sensitive dual-targeting doxorubicin (DOX) carrier to compromise tumor endothelial cells, enhance BBB transportation, and improve drug accumulation in glioma cell...

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Detalles Bibliográficos
Autores principales: Hu, Jiangang, Zhang, Xiang, Wen, Zuhuang, Tan, Ying, Huang, Ning, Cheng, Si, Zheng, Huzhi, Cheng, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342007/
https://www.ncbi.nlm.nih.gov/pubmed/27655664
http://dx.doi.org/10.18632/oncotarget.12047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342007/
https://www.ncbi.nlm.nih.gov/pubmed/27655664
http://dx.doi.org/10.18632/oncotarget.12047

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