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Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients

Tumor profiling of DNA alterations, i.e. gene point mutations, somatic copy number aberrations (CNAs) and structural variants (SVs), improves insight into the molecular pathology of cancer and clinical outcome. Here, associations between genomic aberrations and disease recurrence in stage II and III...

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Detalles Bibliográficos
Autores principales: van den Broek, Evert, Krijgsman, Oscar, Sie, Daoud, Tijssen, Marianne, Mongera, Sandra, van de Wiel, Mark A., Th. Belt, Eric J., den Uil, Sjoerd H., Bril, Herman, Stockmann, Hein B.A.C., Ylstra, Bauke, Carvalho, Beatriz, Meijer, Gerrit A., Fijneman, Remond J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342020/
https://www.ncbi.nlm.nih.gov/pubmed/27729614
http://dx.doi.org/10.18632/oncotarget.12510