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Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients
Tumor profiling of DNA alterations, i.e. gene point mutations, somatic copy number aberrations (CNAs) and structural variants (SVs), improves insight into the molecular pathology of cancer and clinical outcome. Here, associations between genomic aberrations and disease recurrence in stage II and III...
Autores principales: | van den Broek, Evert, Krijgsman, Oscar, Sie, Daoud, Tijssen, Marianne, Mongera, Sandra, van de Wiel, Mark A., Th. Belt, Eric J., den Uil, Sjoerd H., Bril, Herman, Stockmann, Hein B.A.C., Ylstra, Bauke, Carvalho, Beatriz, Meijer, Gerrit A., Fijneman, Remond J.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342020/ https://www.ncbi.nlm.nih.gov/pubmed/27729614 http://dx.doi.org/10.18632/oncotarget.12510 |
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