Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells

Local acidosis is a common feature of allergic, vascular, autoimmune, and cancer diseases. However, few studies have addressed the effect of extracellular pH on the immune response. Here, we analyzed whether low pH could modulate complement-dependent cytotoxicity (CDC) against IgG-coated cells. Usin...

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Detalles Bibliográficos
Autores principales: Dantas, Ezequiel, Díaz, Fernando Erra, Gerber, Pehuén Pereyra, Merlotti, Antonela, Varese, Augusto, Ostrowski, Matías, Sabatté, Juan, Geffner, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342046/
https://www.ncbi.nlm.nih.gov/pubmed/27716623
http://dx.doi.org/10.18632/oncotarget.12412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342046/
https://www.ncbi.nlm.nih.gov/pubmed/27716623
http://dx.doi.org/10.18632/oncotarget.12412

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