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Profiles of miRNAs matched to biology in aromatase inhibitor resistant breast cancer

Aromatase inhibitor (AI) resistance during breast cancer treatment is mimicked by MCF-7:5C (5C) and MCF-7:2A (2A) cell lines that grow spontaneously. Survival signaling is reconfigured but cells are vulnerable to estradiol (E(2))-inducible apoptosis. These model systems have alterations of stress re...

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Detalles Bibliográficos
Autores principales: Hoppe, Reiner, Fan, Ping, Büttner, Florian, Winter, Stefan, Tyagi, Amit K., Cunliffe, Heather, Jordan, V. Craig, Brauch, Hiltrud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342075/
https://www.ncbi.nlm.nih.gov/pubmed/27659519
http://dx.doi.org/10.18632/oncotarget.12103