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Gamma-interferon-inducible, lysosome/endosome-localized thiolreductase, GILT, has anti-retroviral activity and its expression is counteracted by HIV-1

The mechanism by which type II interferon (IFN) inhibits virus replications remains to be identified. Murine leukemia virus (MLV) replication was significantly restricted by γ-IFN, but not human immunodeficiency virus type 1 (HIV-1) replication. Because MLV enters host cells via endosomes, we specul...

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Detalles Bibliográficos
Autores principales: Kubo, Yoshinao, Izumida, Mai, Yashima, Yuka, Yoshii-Kamiyama, Haruka, Tanaka, Yuetsu, Yasui, Kiyoshi, Hayashi, Hideki, Matsuyama, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342076/
https://www.ncbi.nlm.nih.gov/pubmed/27655726
http://dx.doi.org/10.18632/oncotarget.12104