Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-β pathway

miR122 is the prevalent miRNA in adult healthy liver and it is responsible for liver stem cell differentiation towards hepatocyte lineage. Its expression is frequently lost in hepatocellular carcinoma (HCC). We studied the effects of restoring miR122 expression in a distinctive cell line derived fro...

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Detalles Bibliográficos
Autores principales: Boix, Loreto, López-Oliva, Juan Manuel, Rhodes, Ana Carolina, Bruix, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342080/
https://www.ncbi.nlm.nih.gov/pubmed/27612430
http://dx.doi.org/10.18632/oncotarget.11885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342080/
https://www.ncbi.nlm.nih.gov/pubmed/27612430
http://dx.doi.org/10.18632/oncotarget.11885

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