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Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-β pathway
miR122 is the prevalent miRNA in adult healthy liver and it is responsible for liver stem cell differentiation towards hepatocyte lineage. Its expression is frequently lost in hepatocellular carcinoma (HCC). We studied the effects of restoring miR122 expression in a distinctive cell line derived fro...
Autores principales: | Boix, Loreto, López-Oliva, Juan Manuel, Rhodes, Ana Carolina, Bruix, Jordi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342080/ https://www.ncbi.nlm.nih.gov/pubmed/27612430 http://dx.doi.org/10.18632/oncotarget.11885 |
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