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Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential

Pancreatic Ductal Adenocarcinoma (PDAC) is a highly lethal malignancy that responds poorly to current therapeutic modalities. In an effort to develop novel therapeutic strategies, we found downregulation of miR-29 in pancreatic cancer cells, and overexpression of miR-29a sensitized chemotherapeutic...

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Detalles Bibliográficos
Autores principales: Kwon, Jason J., Willy, Jeffrey A., Quirin, Kayla A., Wek, Ronald C., Korc, Murray, Yin, Xiao-Ming, Kota, Janaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342107/
https://www.ncbi.nlm.nih.gov/pubmed/27626694
http://dx.doi.org/10.18632/oncotarget.11928