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Fiber-modified adenovirus-mediated suicide gene therapy can efficiently eliminate bladder cancer cells in vitro and in vivo

Adenovirus-mediated gene therapy is a promising strategy for bladder cancer treatment. However, the loss of the coxsackie and adenovirus receptor (CAR) in bladder cancer cells decreases the infection efficiency of the therapeutic adenovirus. In this study, we constructed an Arg-Gly-Asp (RGD)-modifie...

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Detalles Bibliográficos
Autores principales: Wang, De-Gui, Zhao, Mei-Jun, Liu, Yong-Qiang, Liu, Xiang-Wen, Niu, Hai-Tao, Song, Yan-Feng, Tian, Ying-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342114/
https://www.ncbi.nlm.nih.gov/pubmed/27687590
http://dx.doi.org/10.18632/oncotarget.12324