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MDM4 rs4245739 A > C polymorphism correlates with reduced overall cancer risk in a meta-analysis of 69477 subjects

Mouse double minute 4 (MDM4) is a p53-interacting oncoprotein that plays an important role in the p53 tumor suppressor pathway. The common rs4245739 A > C polymorphism creates a miR-191 binding site in the MDM4 gene transcript. Numerous studies have investigated the association between this MDM4...

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Detalles Bibliográficos
Autores principales: Xu, Chaoyi, Zhu, Jinhong, Fu, Wen, Liang, Zongwen, Song, Shujie, Zhao, Yuan, Lyu, Lihua, Zhang, Anqi, He, Jing, Duan, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342115/
https://www.ncbi.nlm.nih.gov/pubmed/27687591
http://dx.doi.org/10.18632/oncotarget.12326