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MDM4 rs4245739 A > C polymorphism correlates with reduced overall cancer risk in a meta-analysis of 69477 subjects
Mouse double minute 4 (MDM4) is a p53-interacting oncoprotein that plays an important role in the p53 tumor suppressor pathway. The common rs4245739 A > C polymorphism creates a miR-191 binding site in the MDM4 gene transcript. Numerous studies have investigated the association between this MDM4...
Autores principales: | Xu, Chaoyi, Zhu, Jinhong, Fu, Wen, Liang, Zongwen, Song, Shujie, Zhao, Yuan, Lyu, Lihua, Zhang, Anqi, He, Jing, Duan, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342115/ https://www.ncbi.nlm.nih.gov/pubmed/27687591 http://dx.doi.org/10.18632/oncotarget.12326 |
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