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Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma

The infiltration of melanoma tumors by macrophages is often correlated with poor prognosis. However, the molecular signals that regulate the dialogue between malignant cells and the inflammatory microenvironment remain poorly understood. We previously reported an increased expression of sphingosine...

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Detalles Bibliográficos
Autores principales: Mrad, Marguerite, Imbert, Caroline, Garcia, Virginie, Rambow, Florian, Therville, Nicole, Carpentier, Stéphane, Ségui, Bruno, Levade, Thierry, Azar, Rania, Marine, Jean-Christophe, Diab-Assaf, Mona, Colacios, Céline, Andrieu-Abadie, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342129/
https://www.ncbi.nlm.nih.gov/pubmed/27708249
http://dx.doi.org/10.18632/oncotarget.12380