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MDS shows a higher expression of hTERT and alternative splice variants in unactivated T-cells

Telomere instability and telomerase reactivation are believed to play an important role in the development of myelodysplastic syndromes (MDS). Abnormal enzymatic activity of human telomerase reverse transcriptase (hTERT), and its alternative splice variants have been reported to account for deregula...

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Detalles Bibliográficos
Autores principales: Dong, Wen, Wu, Lei, Sun, Houfang, Ren, Xiubao, Epling-Burnette, Pearlie K., Yang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342131/
https://www.ncbi.nlm.nih.gov/pubmed/27655690
http://dx.doi.org/10.18632/oncotarget.12115