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MDS shows a higher expression of hTERT and alternative splice variants in unactivated T-cells
Telomere instability and telomerase reactivation are believed to play an important role in the development of myelodysplastic syndromes (MDS). Abnormal enzymatic activity of human telomerase reverse transcriptase (hTERT), and its alternative splice variants have been reported to account for deregula...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342131/ https://www.ncbi.nlm.nih.gov/pubmed/27655690 http://dx.doi.org/10.18632/oncotarget.12115 |