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Increased gene expression noise in human cancers is correlated with low p53 and immune activities as well as late stage cancer

Gene expression in metazoans is delicately organized. As genetic information transmits from DNA to RNA and protein, expression noise is inevitably generated. Recent studies begin to unveil the mechanisms of gene expression noise control, but the changes of gene expression precision in pathologic con...

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Detalles Bibliográficos
Autores principales: Han, Rongfei, Huang, Guanqun, Wang, Yejun, Xu, Yafei, Hu, Yueming, Jiang, Wenqi, Wang, Tianfu, Xiao, Tian, Zheng, Duo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342140/
https://www.ncbi.nlm.nih.gov/pubmed/27713130
http://dx.doi.org/10.18632/oncotarget.12457