PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma

Although cancer cells are known to be “addicted” to glucose, the effect of glucose in proliferation of these cells remains elusive. Here, we report that upon glucose induction, protein arginine methyltransferase 5 (PRMT5) exerts a profound effect on the G1-S cell cycle progression via directly inter...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Hao, Zhao, Xiaoping, Zhao, Li, Liu, Liu, Li, Jiajin, Jia, Wenzhi, Liu, Jianjun, Huang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342150/
https://www.ncbi.nlm.nih.gov/pubmed/27708221
http://dx.doi.org/10.18632/oncotarget.12351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342150/
https://www.ncbi.nlm.nih.gov/pubmed/27708221
http://dx.doi.org/10.18632/oncotarget.12351

Ejemplares similares