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Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion
Leukocyte trafficking is crucial to facilitate efficient immune responses. Here, we report that the large GTPase dynamin2, which is generally considered to have a key role in endocytosis and membrane remodeling, is an essential regulator of integrin-dependent human T lymphocyte adhesion and migratio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342215/ https://www.ncbi.nlm.nih.gov/pubmed/28273099 http://dx.doi.org/10.1371/journal.pone.0172443 |