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Identification of small molecule inhibitors for influenza a virus using in silico and in vitro approaches

Influenza viruses have acquired resistance to approved neuraminidase-targeting drugs, increasing the need for new drug targets for the development of novel anti-influenza drugs. Nucleoprotein (NP) is an attractive target since it has an indispensable role in virus replication and its amino acid sequ...

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Detalles Bibliográficos
Autores principales: Makau, Juliann Nzembi, Watanabe, Ken, Ishikawa, Takeshi, Mizuta, Satoshi, Hamada, Tsuyoshi, Kobayashi, Nobuyuki, Nishida, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342234/
https://www.ncbi.nlm.nih.gov/pubmed/28273150
http://dx.doi.org/10.1371/journal.pone.0173582