Cargando…
Identification of small molecule inhibitors for influenza a virus using in silico and in vitro approaches
Influenza viruses have acquired resistance to approved neuraminidase-targeting drugs, increasing the need for new drug targets for the development of novel anti-influenza drugs. Nucleoprotein (NP) is an attractive target since it has an indispensable role in virus replication and its amino acid sequ...
Autores principales: | Makau, Juliann Nzembi, Watanabe, Ken, Ishikawa, Takeshi, Mizuta, Satoshi, Hamada, Tsuyoshi, Kobayashi, Nobuyuki, Nishida, Noriyuki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342234/ https://www.ncbi.nlm.nih.gov/pubmed/28273150 http://dx.doi.org/10.1371/journal.pone.0173582 |
Ejemplares similares
-
A Quinolinone Compound Inhibiting the Oligomerization of Nucleoprotein of Influenza A Virus Prevents the Selection of Escape Mutants
por: Makau, Juliann Nzembi, et al.
Publicado: (2020) -
Design and Development of an HBT-Based Ratiometric
Fluorescent Probe to Monitor Stress-Induced Premature Senescence
por: Makau, Juliann Nzembi, et al.
Publicado: (2020) -
Structure-based drug discovery for combating influenza virus by targeting the PA–PB1 interaction
por: Watanabe, Ken, et al.
Publicado: (2017) -
Novel and potent antimicrobial effects of caspofungin on drug-resistant Candida and bacteria
por: Sumiyoshi, Makoto, et al.
Publicado: (2020) -
Structure-Based Drug Discovery for Prion Disease Using a Novel Binding Simulation
por: Ishibashi, Daisuke, et al.
Publicado: (2016)