Reversible modulation of SIRT1 activity in a mouse strain

The SIRT1 protein deacetylase is reported to have a remarkably wide spectrum of biological functions affecting such varied processes as aging, cancer, metabolism, neurodegeneration and immunity. However, the SIRT1 literature is also full of contradictions. To help establish the role(s) of SIRT1 in t...

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Detalles Bibliográficos
Autores principales: Clark-Knowles, Katherine V., He, Xiaohong, Jardine, Karen, Coulombe, Josée, Dewar-Darch, Danielle, Caron, Annabelle Z., Gray, Douglas A., McBurney, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342236/
https://www.ncbi.nlm.nih.gov/pubmed/28273169
http://dx.doi.org/10.1371/journal.pone.0173002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342236/
https://www.ncbi.nlm.nih.gov/pubmed/28273169
http://dx.doi.org/10.1371/journal.pone.0173002

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