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Reversible modulation of SIRT1 activity in a mouse strain
The SIRT1 protein deacetylase is reported to have a remarkably wide spectrum of biological functions affecting such varied processes as aging, cancer, metabolism, neurodegeneration and immunity. However, the SIRT1 literature is also full of contradictions. To help establish the role(s) of SIRT1 in t...
Autores principales: | Clark-Knowles, Katherine V., He, Xiaohong, Jardine, Karen, Coulombe, Josée, Dewar-Darch, Danielle, Caron, Annabelle Z., Gray, Douglas A., McBurney, Michael W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342236/ https://www.ncbi.nlm.nih.gov/pubmed/28273169 http://dx.doi.org/10.1371/journal.pone.0173002 |
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