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Altering the N-terminal arms of the polymerase manager protein UmuD modulates protein interactions

Escherichia coli cells that are exposed to DNA damaging agents invoke the SOS response that involves expression of the umuD gene products, along with more than 50 other genes. Full-length UmuD is expressed as a 139-amino-acid protein, which eventually cleaves its N-terminal 24 amino acids to form Um...

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Detalles Bibliográficos
Autores principales: Murison, David A., Ollivierre, Jaylene N., Huang, Qiuying, Budil, David E., Beuning, Penny J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342242/
https://www.ncbi.nlm.nih.gov/pubmed/28273172
http://dx.doi.org/10.1371/journal.pone.0173388