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Dose-dependent genotype effects of BDNF Val66Met polymorphism on default mode network in early stage Alzheimer's disease

In humans, brain-derived neurotrophic factor (BDNF) has been shown to play a pivotal role in neurocognition, and its gene contains a functional polymorphism (Val66Met) that may explain individual differences in brain volume and memory-related activity. In this study, we enrolled 186 Alzheimer's...

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Detalles Bibliográficos
Autores principales: Lin, Pin-Hsuan, Tsai, Shih-Jen, Huang, Chi-Wei, Mu-En, Liu, Hsu, Shih-Wei, Lee, Chen-Chang, Chen, Nai-Ching, Chang, Ya-Ting, Lan, Min-Yu, Chang, Chiung-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342335/
https://www.ncbi.nlm.nih.gov/pubmed/27494844
http://dx.doi.org/10.18632/oncotarget.11027