Cardiac fibrosis in mouse expressing DsRed tetramers involves chronic autophagy and proteasome degradation insufficiency

Proteinopathy in the heart which often manifests excessive misfolded/aggregated proteins in cardiac myocytes can result in severe fibrosis and heart failure. Here we developed a mouse model, which transgenically express tetrameric DsRed, a red fluorescent protein (RFP), in an attempt to mimic the pa...

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Detalles Bibliográficos
Autores principales: Chen, Tsung-Hsien, Chen, Mei-Ru, Chen, Tzu-Yin, Wu, Tzu-Chin, Liu, Shan-Wen, Hsu, Ching-Han, Liou, Gan-Guang, Kao, Yu-Ying, Dong, Guo-Chung, Chu, Pao-Hsien, Liao, Jiunn-Wang, Lin, Kurt Ming-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342341/
https://www.ncbi.nlm.nih.gov/pubmed/27494843
http://dx.doi.org/10.18632/oncotarget.11026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342341/
https://www.ncbi.nlm.nih.gov/pubmed/27494843
http://dx.doi.org/10.18632/oncotarget.11026

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