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NLRP3 inflammasome activation is involved in Ang II-induced kidney damage via mitochondrial dysfunction

Growing evidence has shown that NLRP3 inflammasome activation promotes the development of tubulointerstitial inflammation and progression of renal injury. We previously found that mitochondrial dysfunction is a critical determinant for the activation of NLRP3 inflammasome in albumin-overload rats. A...

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Detalles Bibliográficos
Autores principales: Wen, Yi, Liu, Yiran, Tang, Taotao, Lv, Linli, Liu, Hong, Ma, Kunling, Liu, Bicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342342/
https://www.ncbi.nlm.nih.gov/pubmed/27509058
http://dx.doi.org/10.18632/oncotarget.11091