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Inherent low Erk and p38 activity reduce Fas Ligand expression and degranulation in T helper 17 cells leading to activation induced cell death resistance

Activation Induced Cell Death of T helper cells is central to maintaining immune homeostasis and a perturbation often manifests in aberrant T helper cells that is associated with immunopathologies. Significant presence of T cells positive for IL-17A (Th17) and dual positive for IFN-γ/IL-17A (Th1/Th1...

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Detalles Bibliográficos
Autores principales: Peroumal, Doureradjou, Abimannan, Thiruvaimozhi, Tagirasa, Ravichandra, Parida, Jyothi Ranjan, Singh, Santosh Kumar, Padhan, Prasantha, Devadas, Satish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342346/
https://www.ncbi.nlm.nih.gov/pubmed/27486885
http://dx.doi.org/10.18632/oncotarget.10913