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Inherent low Erk and p38 activity reduce Fas Ligand expression and degranulation in T helper 17 cells leading to activation induced cell death resistance
Activation Induced Cell Death of T helper cells is central to maintaining immune homeostasis and a perturbation often manifests in aberrant T helper cells that is associated with immunopathologies. Significant presence of T cells positive for IL-17A (Th17) and dual positive for IFN-γ/IL-17A (Th1/Th1...
Autores principales: | Peroumal, Doureradjou, Abimannan, Thiruvaimozhi, Tagirasa, Ravichandra, Parida, Jyothi Ranjan, Singh, Santosh Kumar, Padhan, Prasantha, Devadas, Satish |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342346/ https://www.ncbi.nlm.nih.gov/pubmed/27486885 http://dx.doi.org/10.18632/oncotarget.10913 |
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