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Myeloid cell expressed proprotein convertase FURIN attenuates inflammation

The proprotein convertase enzyme FURIN processes immature pro-proteins into functional end- products. FURIN is upregulated in activated immune cells and it regulates T-cell dependent peripheral tolerance and the Th1/Th2 balance. FURIN also promotes the infectivity of pathogens by activating bacteria...

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Detalles Bibliográficos
Autores principales: Cordova, Zuzet Martinez, Grönholm, Anna, Kytölä, Ville, Taverniti, Valentina, Hämäläinen, Sanna, Aittomäki, Saara, Niininen, Wilhelmiina, Junttila, Ilkka, Ylipää, Antti, Nykter, Matti, Pesu, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342350/
https://www.ncbi.nlm.nih.gov/pubmed/27527873
http://dx.doi.org/10.18632/oncotarget.11106